Wellpride Blog

Up to 60% of all equine lameness cases are caused by osteoarthritis, the dreaded joint disease that eats away at cartilage. While there is no known cure for osteoarthritis, making small diet changes can be one of the simplest and most effective means of treating your horse’s inflamed joints.

Wellpride founder and omega-3 specialist Dr. Anne-Marie Chalmers advocates adding fish oil to a horse’s daily feed.

“Omega-3 is a natural anti-inflammation agent, that all of us – horses and humans – need,” said Dr. Chalmers. “It works on the same biochemical pathways as pain-relieving drugs, and doesn’t create nasty side effects, like gastrointestinal problems.”

Omega-3, an essential fatty acid found most abundantly in fish, has been making news in human medicine for its pain relief benefits. Numerous studies have found that omega-3 fish oil reduces the activity of cartilage-destructing enzymes and can decrease the inflammation response.

While the research on omega-3 in horses is still scant, one study showed that horses fed omega-3 fatty acids needed significantly less non-steroidal anti-inflammatory drugs (NSAID).

Dr. Chalmers explains that an omega-6/omega-3 imbalance is at the heart of many osteoarthritis cases.

“In the past, horses were sent out to pasture more frequently, and they consumed enough omega-3 through the steady intake of grass,” said Dr. Chalmers. “Today, horse diets have shifted towards processed foods and corn products that are filled with omega-6.”

Also in the essential fatty acid family, omega-6 counteracts omega-3 by creating inflammation. When the horse consumes more omega-6 than omega-3, he has a higher risk for developing a host of inflammatory diseases, including arthritis.

Besides osteoarthritis, equine lameness can be caused by anything from bruising to bad shoeing to tying up. But for inflammation problems, Dr. Chalmers suggests a healthy dose of fish oil to fight the lameness.

Sources:

“Horse Lameness (Equine Lameness).” PetHealth101 – Your Dog, Cat and Pet Health Resource. Web. 05 Aug. 2010.

Martinsen, Bo. “Arthritis.” Wellpride Omega-3 Fish Oil for Horses. Wellpride. Web. 05 Aug. 2010. 

Oke, Stacey. “Osteoarthritis: Not Just an ‘Old-Horse Disease’” The Horse Apr. 2010: 35-40.

The delicate structure of the horse’s legs and hoofs makes theses areas easily prone to problems. Of all the hoof problems a horse can suffer from, laminitis is the most worrisome.

Factors involved in lamellae separation

The passive vascular congestion seen during laminitis in horses is thought to be mediated by chemicals produced from the cell membrane in response to either metabolic or physical irritation. This painful condition causes the separation of the sensitive lamellae serving as a bridge between the pedal bone to the inner hoof wall. The severity of the process depends on the amount of inflammation, the degree of blood flow reduction, clot formation and the amount of mechanical stress superimposed on the lamellae.

The painful process

The above mentioned pathological changes are basically mediated from potent chemical mediators derived from the omega-6 fatty acid family. Elevated levels of omega-6, at the expense of omega-3, result in an eicosanoid precursor pool dominated by one main omega-6 family member, arachidonic acid. Arachidonic acid is the building block for prostaglandin E2 and leukotrieneB (LTB4). These two substances activate pro-inflammatory reactions producing swelling, heat and pain in the afflicted area. These mediators are then capable of destroying key components of the lamellar attachment. This may lead to painful tearing of the support structure suspending the pedal bone within the hoof. If laminitis is not treated promptly, it can lead to a final downward rotation of pedal bone as a consequence of its separations from the lamellae.

Predisposing factors

We know the predisposing factors for the development of laminitis in horses include any inflammatory processes. Usually these are relation to the gastrointestinal tract, reproductive organs (metritis, retained placenta), respiratory system (pleuropneumonia), endotoxemia and even traumatic factors such as prolonged or excessive weight in one or more limbs.

EPA and DHA inhibit pro-inflammatory agents

Dr Gerard Hornstra, Professor of Experimental Nutrition at the Maastricht University explains, EPA and DHA inhibit eicosanoid synthesis from arachidonic acid and cytokine production from monocytes/macrophages. Although omega-3 EPA promotes the formation of prostaglandin E3 and leukotriene B5, these eicosanoids are far less active as pro-inflammatory agents than the corresponding derivatives of arachidonic acid. It is then thought the active and potent anti-inflammatory mediators derived from omega-3′s EPA and DHA will reduce the risk of exacerbated inflammatory responses when any predisposing factors develop. In addition they have a positive regulatory effect on the vascular bed and their pro-coagulant effects are also much less active.

Omega-3 reduces risk of inflammation

Increase supplementation of the horses? diet with omega-3 essential fatty acids results in a partial and progressive substitution of omega-6 derivatives in the cell membrane. As the amount of omega-6 decreases and the amount of omega-3 increases, the risks of exacerbated inflammatory responses are reduced.

Many testimonials exist from horse people about the radical improvement of horses with chronic founder after a few weeks of supplementation with omega-3 essential fatty acids with EPA/DHA.

Dr. Bo Martinsen